Rola czynników zakaźnych w chorobach neurodegeneracyjnych
1. Wprowadzenie. 2. Choroba Alzheimera. 2.1. Chlamydophila pneumoniae. 2.2. Wirus opryszczki pospolitej typu 1. 2.3. Krętki. 2.4. Helicobacter pylori. 3. Choroba Parkinsona. 3.1. Zespół nabytego niedoboru odporności (AIDS). 3.2. Toxoplasma gondii. 4. Stwardnienie rozsiane. 4.1. Wirus Epsteina-Barr. 4.2. Wirus Torque teno. 4.3. Ludzki Herpeswirus typu 6. 4.4. Chlamydophila pneumoniae. 5. Podsumowanie
Abstract: Pathogens are possible risk factors for chronic degenerative diseases of the nervous system. This paper summarizes the evidence of infectious agents’ relationship with neurodegenerative diseases and current knowledge about the role of pathogens in the modulation of immunological mechanism in the most common degenerative diseases: Alzheimer disease, Parkinson disease and multiple sclerosis. Infections with Chlamydia pneumoniae, Herpes simplex virus type 1, spirochaete and Helicobacter pylori may constitute risk factors for the Alzheimer disease. Human immunodeficiency virus and Toxoplasma gondii in the brain can cause parkinsonism. Epstein-Barr virus and co-infection with Torque teno virus as well as Human herpes virus type 6 and Chlamydia pneumoniae may play a role in the pathogenesis of multiple sclerosis.
1. Introduction. 2. Alzheimer’s disease. 2.1. Chlamydophila pneumoniae. 2.2. Herpes simplex virus 1. 2.3. Spirochetes. 2.4. Helicobacter pylori. 3. Parkinson’s disease. 3.1. Acquired immunodeficiency syndrome (AIDS). 3.2. Toxoplasma gondii. 4. Multiple sclerosis. 4.1. Epstein- -Barr virus. 4.2. Torque teno virus. 4.3. Human Herpesvirus 6. 4.4. Chlamydophila pneumoniae. 5. Summary
